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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CUL5
All Species:
27.58
Human Site:
S12
Identified Species:
43.33
UniProt:
Q93034
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q93034
NP_003469.2
780
90955
S12
N
L
L
K
N
K
G
S
L
Q
F
E
D
K
W
Chimpanzee
Pan troglodytes
XP_001137909
721
84087
S12
N
L
L
K
N
K
G
S
L
Q
F
E
D
K
W
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_546540
811
94684
S43
F
F
F
K
N
K
G
S
L
Q
F
E
D
K
W
Cat
Felis silvestris
Mouse
Mus musculus
Q9D5V5
780
90956
S12
N
L
L
K
N
K
G
S
L
Q
F
E
D
K
W
Rat
Rattus norvegicus
Q9JJ31
780
90872
S12
N
L
L
K
N
K
G
S
L
Q
F
E
D
K
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508663
779
91022
E15
N
K
G
S
L
Q
F
E
D
K
W
D
F
M
R
Chicken
Gallus gallus
XP_417163
809
94020
S41
S
L
L
S
N
K
G
S
L
Q
F
E
D
K
W
Frog
Xenopus laevis
Q6GPF3
768
88937
P22
K
M
R
I
R
A
F
P
M
T
M
D
E
K
Y
Zebra Danio
Brachydanio rerio
XP_001922879
780
90814
S12
N
L
L
K
N
K
G
S
L
Q
F
E
D
K
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24311
774
89493
L13
N
S
Q
T
T
Q
K
L
V
N
L
D
D
I
W
Honey Bee
Apis mellifera
XP_623958
789
91733
Q14
K
V
P
M
D
K
S
Q
F
T
F
E
D
K
W
Nematode Worm
Caenorhab. elegans
Q23639
765
88890
L18
D
P
I
V
H
A
L
L
H
Q
K
S
V
T
P
Sea Urchin
Strong. purpuratus
XP_787630
787
91852
Q24
M
L
K
Q
D
K
T
Q
P
Q
F
E
D
R
W
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q94AH6
738
86284
Y14
D
L
E
Q
G
W
D
Y
M
Q
T
G
I
T
K
Baker's Yeast
Sacchar. cerevisiae
Q12018
815
93926
N23
N
F
I
E
P
G
I
N
Q
I
L
G
N
E
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.4
N.A.
95.8
N.A.
98.4
98.7
N.A.
98.8
95.6
27.3
95.1
N.A.
29.7
72.3
51.4
72.9
Protein Similarity:
100
92.4
N.A.
96
N.A.
99.6
99.6
N.A.
99.2
96.1
50.2
98.3
N.A.
51.2
83.4
69.3
84.5
P-Site Identity:
100
100
N.A.
80
N.A.
100
100
N.A.
6.6
86.6
6.6
100
N.A.
20
40
6.6
46.6
P-Site Similarity:
100
100
N.A.
80
N.A.
100
100
N.A.
33.3
93.3
40
100
N.A.
40
53.3
26.6
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
24.2
23.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
48.2
44.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
14
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
14
0
0
0
14
0
7
0
7
0
0
20
67
0
0
% D
% Glu:
0
0
7
7
0
0
0
7
0
0
0
60
7
7
0
% E
% Phe:
7
14
7
0
0
0
14
0
7
0
60
0
7
0
0
% F
% Gly:
0
0
7
0
7
7
47
0
0
0
0
14
0
0
0
% G
% His:
0
0
0
0
7
0
0
0
7
0
0
0
0
0
0
% H
% Ile:
0
0
14
7
0
0
7
0
0
7
0
0
7
7
0
% I
% Lys:
14
7
7
40
0
60
7
0
0
7
7
0
0
60
14
% K
% Leu:
0
54
40
0
7
0
7
14
47
0
14
0
0
0
0
% L
% Met:
7
7
0
7
0
0
0
0
14
0
7
0
0
7
0
% M
% Asn:
54
0
0
0
47
0
0
7
0
7
0
0
7
0
0
% N
% Pro:
0
7
7
0
7
0
0
7
7
0
0
0
0
0
7
% P
% Gln:
0
0
7
14
0
14
0
14
7
67
0
0
0
0
0
% Q
% Arg:
0
0
7
0
7
0
0
0
0
0
0
0
0
7
7
% R
% Ser:
7
7
0
14
0
0
7
47
0
0
0
7
0
0
0
% S
% Thr:
0
0
0
7
7
0
7
0
0
14
7
0
0
14
0
% T
% Val:
0
7
0
7
0
0
0
0
7
0
0
0
7
0
0
% V
% Trp:
0
0
0
0
0
7
0
0
0
0
7
0
0
0
67
% W
% Tyr:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _